Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Meperidine
Drug ID BADD_D01384
Description A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Indications and Usage Used to control moderate to severe pain.
Marketing Status approved
ATC Code N02AB02
DrugBank ID DB00454
KEGG ID D08343
MeSH ID D008614
PubChem ID 4058
TTD Drug ID D00UYE
NDC Product Code Not Available
UNII 9E338QE28F
Synonyms Meperidine | Pethidine | Isonipecain | Dolsin | Dolosal | Dolin | Operidine EPJ-I | Operidine EPJ I | Dolantin | Dolargan | Meperidine Hydrochloride | Lidol | Lydol | Demerol | Dolcontral
Chemical Information
Molecular Formula C15H21NO2
CAS Registry Number 57-42-1
SMILES CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Injection site erythema23.03.06.015; 12.07.03.001; 08.02.03.0010.001666%Not Available
Injection site inflammation12.07.03.009; 08.02.03.008--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Laryngospasm22.04.02.002--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Libido decreased21.03.02.005; 19.08.03.001--
Loss of consciousness17.02.04.0040.002651%Not Available
Miosis06.05.03.003; 17.02.11.002--Not Available
Mood swings19.04.03.001--Not Available
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.005--Not Available
Mydriasis06.05.03.004; 17.02.11.003--Not Available
Myoclonus17.02.05.008--Not Available
Myopathy15.05.05.001--Not Available
Nasal congestion22.04.04.001--
Nausea07.01.07.0010.089986%
Neurotoxicity12.03.01.011; 17.02.10.002--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Palpitations02.11.04.012--
Paraesthesia23.03.03.094; 17.02.06.005--
Paralysis17.01.04.0040.000757%Not Available
Paranoia19.05.01.005--Not Available
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.017--
Phlebitis24.12.03.004; 12.02.01.002--
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