Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mercaptoethanesulfonic acid
Drug ID BADD_D01391
Description Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Indications and Usage Mesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Marketing Status approved; investigational
ATC Code R05CB05; V03AF01
DrugBank ID DB09110
KEGG ID D01459
MeSH ID D015080
PubChem ID 598
TTD Drug ID D0C3YQ
NDC Product Code Not Available
UNII VHD28S0H7F
Synonyms Mesna | Mesnum | Sodium 2-Mercaptoethanesulphonate | 2-Mercaptoethanesulphonate, Sodium | Ethanesulfonic acid, 2-mercapto-, monosodium salt | ASTA-D 7093 | ASTA D 7093 | ASTAD 7093 | Coenzyme M | MESNA-cell | MESNA cell | Mesnex | 2-Mercaptoethanesulfonate | 2 Mercaptoethanesulfonate | Mistabron | Mistabronco | Mucofluid | Mitexan | UCB-3983 | UCB 3983 | UCB3983 | Uromitexan | Ziken
Chemical Information
Molecular Formula C2H6O3S2
CAS Registry Number 3375-50-6
SMILES C(CS(=O)(=O)O)S
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Paraesthesia23.03.03.094; 17.02.06.005--
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Photophobia17.17.02.006; 06.01.01.004--
Platelet count decreased13.01.04.001--
Pleuritic pain22.12.01.007--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Tachypnoea22.02.01.014--Not Available
Thrombocytopenia01.08.01.002--Not Available
Vomiting07.01.07.003--
Musculoskeletal discomfort15.03.04.001--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
Faeces soft07.01.03.008--Not Available
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