Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mesna
Drug ID BADD_D01398
Description Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Indications and Usage Mesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Marketing Status approved; investigational
ATC Code R05CB05; V03AF01
DrugBank ID DB09110
KEGG ID D01459
MeSH ID D015080
PubChem ID 23662354
TTD Drug ID D0C3YQ
NDC Product Code 15308-0715; 0143-9260; 10019-953; 72643-007; 58623-0039; 0338-1305; 67108-3565; 0338-1307; 63323-733; 25021-201; 62778-304; 10019-951
UNII NR7O1405Q9
Synonyms Mesna | Mesnum | Sodium 2-Mercaptoethanesulphonate | 2-Mercaptoethanesulphonate, Sodium | Ethanesulfonic acid, 2-mercapto-, monosodium salt | ASTA-D 7093 | ASTA D 7093 | ASTAD 7093 | Coenzyme M | MESNA-cell | MESNA cell | Mesnex | 2-Mercaptoethanesulfonate | 2 Mercaptoethanesulfonate | Mistabron | Mistabronco | Mucofluid | Mitexan | UCB-3983 | UCB 3983 | UCB3983 | Uromitexan | Ziken
Chemical Information
Molecular Formula C2H5NaO3S2
CAS Registry Number 19767-45-4
SMILES C(CS(=O)(=O)[O-])S.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cough22.02.03.001--
Dehydration14.05.05.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Electrocardiogram ST segment elevation13.14.05.025--Not Available
Erythema23.03.06.001--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Flushing24.03.01.002; 08.01.03.025; 23.06.05.003--
Granulocytopenia01.02.03.003--Not Available
Haematuria24.07.01.047; 20.02.01.006; 21.10.01.018--
Headache17.14.01.001--
Heart rate increased13.14.04.002--Not Available
Hyperaesthesia23.03.03.080; 17.02.06.004--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypokalaemia14.05.03.002--
Hypotension24.06.03.002--
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