Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methohexital
Drug ID BADD_D01416
Description An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Indications and Usage Methohexital is indicated for use as an intravenous anaesthetic. It has also been commonly used to induce deep sedation.
Marketing Status approved
ATC Code N01AF01; N05CA15
DrugBank ID DB00474
KEGG ID D04985
MeSH ID D008723
PubChem ID 9034
TTD Drug ID D0S8TD
NDC Product Code 72643-021
UNII E5B8ND5IPE
Synonyms Methohexital | Methohexitone | Brevimytal Natrium | Natrium, Brevimytal | Brietal-Sodium | Brietal Sodium | Methohexital Sodium | Sodium, Methohexital | Methohexital, Monosodium Salt | Monosodium Salt Methohexital | Brevital | Brietal
Chemical Information
Molecular Formula C14H18N2O3
CAS Registry Number 151-83-7
SMILES CCC#CC(C)C1(C(=O)NC(=O)N(C1=O)C)CC=C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Bronchospasm22.03.01.004; 10.01.03.012--
Cardio-respiratory arrest22.02.06.007; 02.03.04.002--Not Available
Delirium19.13.02.001--
Drug ineffective08.06.01.0060.007773%Not Available
Dyspnoea02.11.05.003; 22.02.01.004--
Erythema23.03.06.001--Not Available
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hiccups22.12.01.001; 07.01.06.009--
Hyperkinesia17.01.02.008--Not Available
Hypotension24.06.03.002--
Injection site pain08.02.03.010; 12.07.03.011--Not Available
Laryngospasm22.04.02.002--
Liver function test abnormal13.03.04.030--Not Available
Muscle twitching15.05.03.005--Not Available
Nausea07.01.07.001--
Pruritus23.03.12.001--
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Tachycardia02.03.02.007--Not Available
Thrombophlebitis24.01.02.001--Not Available
Urticaria10.01.06.001; 23.04.02.001--
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