Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methsuximide
Drug ID BADD_D01422
Description Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Indications and Usage For the control of absence (petit mal) seizures that are refractory to other drugs.
Marketing Status approved
ATC Code N03AD03
DrugBank ID DB05246
KEGG ID D00404
MeSH ID C100286
PubChem ID 6476
TTD Drug ID D08EOD
NDC Product Code 0071-0525; 58159-063; 70954-228
UNII 0G76K8X6C0
Synonyms methsuximide | mesuximide | N,2-dimethyl-2-phenylsuccinimide | mesuximid | methsuximide, (+-)-isomer | Celontin | Petinutin | methsuximide, (+)-isomer | methsuximide, (-)-isomer
Chemical Information
Molecular Formula C12H13NO2
CAS Registry Number 77-41-8
SMILES CC1(CC(=O)N(C1=O)C)C2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Aggression19.05.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Eosinophilia01.02.04.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Hallucination, auditory19.10.04.004--Not Available
Headache17.14.01.001--
Hiccups22.12.01.001; 07.01.06.009--
Hyperaemia24.03.02.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Irritability08.01.03.011; 19.04.02.013--
Leukopenia01.02.02.001--Not Available
Mental impairment19.21.02.003; 17.03.03.002--Not Available
Monocytosis01.02.01.004--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Pancytopenia01.03.03.003--Not Available
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.017--
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