Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methyl aminolevulinate hydrochloride
Drug ID BADD_D01424
Description Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Indications and Usage For topical use, in combination with 570 to 670 nm wavelength red light illumination, in the treatment of non-hyperkeratotic actinic keratoses of the face and scalp in immunocompetent patients when used in conjunction with lesion preparation (debridement using a sharp dermal curette).
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB00992
KEGG ID D04988
MeSH ID C475457
PubChem ID 157921
TTD Drug ID Not Available
NDC Product Code 46016-7940
UNII 7S73606O1A
Synonyms methyl 5-aminolevulinate | MAOP cpd | methyl aminolaevulinate | Metvix
Chemical Information
Molecular Formula C6H12ClNO3
CAS Registry Number 79416-27-6
SMILES COC(=O)CCC(=O)CN.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001--Not Available
Rash pustular23.03.10.003; 11.01.12.002--
Scab23.03.03.004--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin hyperpigmentation23.05.01.003--
Skin infection11.01.12.003; 23.11.04.007--
Skin ulcer24.04.03.007; 23.07.03.003--
Skin warm23.03.03.014--Not Available
Squamous cell carcinoma16.16.01.002--Not Available
Swelling08.01.03.015--Not Available
Ulcer08.03.06.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vitreous detachment12.01.04.005; 06.09.01.002--Not Available
Application site eczema23.03.04.015; 12.07.01.019; 08.02.01.019--Not Available
Skin tightness23.03.03.018--Not Available
Application site discharge23.03.03.049; 12.07.01.039; 08.02.01.039--Not Available
Skin burning sensation23.03.03.021; 17.02.06.009--Not Available
Skin oedema23.06.04.001--Not Available
Skin haemorrhage24.07.01.103; 23.06.07.001--Not Available
Sensitisation10.02.01.012; 08.01.05.009--Not Available
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