| Pharmaceutical Information |
| Drug Name |
Methysergide maleate |
| Drug ID |
BADD_D01440 |
| Description |
An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome. |
| Indications and Usage |
For the treatment of vascular headache |
| Marketing Status |
approved |
| ATC Code |
N02CA04 |
| DrugBank ID |
DB00247
|
| KEGG ID |
D00681
|
| MeSH ID |
D008784
|
| PubChem ID |
5281073
|
| TTD Drug ID |
D0O6GC
|
| NDC Product Code |
Not Available |
| UNII |
2U7H1466GH
|
| Synonyms |
Methysergide | Dimethylergometrin | Methylmethylergonovine | UML-491 | UML 491 | UML491 | Sansert | Deseril | Désernil-Sandoz | Désernil Sandoz | Desril | Methysergide Dimaleate | Dimaleate, Methysergide | Methysergide Maleate | Maleate, Methysergide |
|
| Chemical Information |
| Molecular Formula |
C25H31N3O6 |
| CAS Registry Number |
129-49-7 |
| SMILES |
CCC(CO)NC(=O)C1CN(C2CC3=CN(C4=CC=CC(=C34)C2=C1)C)C.C(=CC(=O)O)C(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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