Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Metipranolol
Drug ID BADD_D01441
Description A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Indications and Usage Indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open angle glaucoma.
Marketing Status approved
ATC Code S01ED04
DrugBank ID DB01214
KEGG ID D02374
MeSH ID D014290
PubChem ID 31477
TTD Drug ID D0L5FY
NDC Product Code Not Available
UNII X39AL81KEB
Synonyms Metipranolol | Methypranol | Trimepranol | 1-(4-Acetoxy-2,3,5-Trimethylphenoxy)-3-Isopropylamino-2-Propanol | Disorat
Chemical Information
Molecular Formula C17H27NO4
CAS Registry Number 22664-55-7
SMILES CC1=CC(=C(C(=C1OC(=O)C)C)C)OCC(CNC(C)C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Angina pectoris24.04.04.002; 02.02.02.002--
Anxiety19.06.02.002--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Blepharitis23.03.04.012; 06.04.04.001--Not Available
Bradycardia02.03.02.002--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Conjunctivitis11.01.06.012; 06.04.01.002--
Cough22.02.03.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.11.04.006--
Dyspnoea02.11.05.003; 22.02.01.004--
Epistaxis24.07.01.005; 22.04.03.001--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Lacrimation increased06.08.02.004--
Migraine17.14.02.001; 24.03.05.003--Not Available
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Palpitations02.11.04.012--
Photophobia17.17.02.006; 06.01.01.004--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
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