| Pharmaceutical Information |
| Drug Name |
Metolazone |
| Drug ID |
BADD_D01444 |
| Description |
A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss. |
| Indications and Usage |
For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class. |
| Marketing Status |
approved |
| ATC Code |
C03BA08 |
| DrugBank ID |
DB00524
|
| KEGG ID |
D00431
|
| MeSH ID |
D008788
|
| PubChem ID |
4170
|
| TTD Drug ID |
D01WLC
|
| NDC Product Code |
64330-115; 46708-532; 51407-431; 51407-432; 0527-2217; 72888-053; 72888-054; 76385-136; 10135-765; 50742-351; 51079-023; 60687-624; 62332-532; 71406-113; 71406-115; 65392-2201; 0185-0055; 51079-024; 63629-7875; 0527-2215; 71335-1944; 72888-052; 69575-4023; 60687-635; 0378-6172; 69292-562; 0527-2216; 71406-114; 46708-534; 63629-8733; 71610-285; 76385-137; 43353-999; 0185-5050; 62332-534; 69292-564; 69292-566; 69766-067; 0185-5600; 50742-350; 51407-433; 63629-8722; 0378-6173; 0904-6916; 17381-254; 0904-7138; 10135-767; 43353-931; 50742-349; 62332-533; 0378-6174; 71610-142; 76385-138; 43353-890; 0904-7139; 10135-766; 46708-533 |
| UNII |
TZ7V40X7VX
|
| Synonyms |
Metolazone | Microx | Mykrox | Zaroxolyn | Diulo | SR-720-22 | SR 720 22 | SR72022 |
|
| Chemical Information |
| Molecular Formula |
C16H16ClN3O3S |
| CAS Registry Number |
17560-51-9 |
| SMILES |
CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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