| Drug Name |
Metoprolol tartrate |
| Drug ID |
BADD_D01447 |
| Description |
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative.[T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.[A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] |
| Indications and Usage |
Metoprolol is indicated for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation, atrial flutter and hypertension.[A175141]
Some off-label uses of metoprolol include supraventricular tachycardia and thyroid storm.[A175141]
All the indications of metoprolol are part of cardiovascular diseases. These conditions correspond to a number of diseases that involve the function of the heart and blood vessels. The underlying causes of these conditions are variable and can be due to genetic disposition, lifestyle decisions such as smoking, obesity, diet, and lack of exercise, and comorbidity with other conditions such as diabetes. The cardiovascular diseases are the leading cause of death on a global scale.[L5533] |
| Marketing Status |
approved; investigational |
| ATC Code |
C07AB02 |
| DrugBank ID |
DB00264
|
| KEGG ID |
D00601
|
| MeSH ID |
D008790
|
| PubChem ID |
441308
|
| TTD Drug ID |
D0I2MK
|
| NDC Product Code |
72888-006; 72888-101; 57451-1163; 65862-063; 30698-459; 36000-033; 50090-1979; 51662-1365; 52817-358; 55154-4451; 55154-5356; 55154-5512; 55700-646; 58118-0361; 60760-243; 60760-295; 60760-566; 63187-532; 0378-4594; 68071-2783; 68788-7832; 68788-8249; 70882-132; 70934-351; 70934-719; 71205-701; 71335-0607; 71335-1600; 71335-2164; 71335-9745; 76420-054; 82727-001; 65862-064; 42708-147; 50090-6083; 51079-801; 55154-4745; 57237-100; 57664-506; 58118-1062; 0378-4593; 67296-0729; 68071-3337; 71335-0743; 71335-1157; 71335-9716; 71872-7124; 71872-7225; 71872-7226; 72611-740; 52423-0915; 52932-0710; 43063-927; 43063-938; 0143-9873; 51407-110; 51655-281; 52817-362; 53808-1117; 57664-162; 63187-609; 0378-0032; 0409-2016; 70882-133; 70934-500; 71335-0241; 71335-1146; 71610-137; 71610-556; 55154-1557; 55154-4752; 63187-174; 68645-190; 70518-3475; 71610-184; 0615-8016; 71872-7283; 65862-062; 50090-5070; 51407-111; 51655-514; 53002-1005; 55154-2126; 63187-252; 63187-600; 70934-736; 71610-147; 71872-7155; 72888-005; 51655-534; 52817-360; 53002-1026; 57664-167; 57664-477; 61919-415; 62584-267; 63187-103; 63629-8101; 67544-387; 68071-2757; 68071-4755; 68788-8207; 68788-8211; 70518-2193; 70518-2437; 71335-0192; 71610-186; 62991-2897; 65862-416; 72640-016; 35356-782; 42708-041; 50090-2149; 50090-2207; 51662-1478; 57237-102; 57664-166; 62584-266; 68071-4880; 68083-131; 68788-7690; 71610-138; 72888-004; 12666-0009; 38779-0578; 30698-458; 49999-575; 51079-255; 51655-884; 52817-359; 63629-8103; 0378-0018; 68071-2877; 68071-5236; 0409-1778; 68645-191; 70518-2615; 71335-1142; 71610-158; 71610-443; 72888-023; 51552-0915; 52932-0743; 63415-0022; 42708-110; 43063-821; 55154-4790; 57237-101; 62584-265; 0378-0047; 70518-0381; 70518-3293; 70518-3503; 70934-390; 71610-080; 71610-565; 72266-122; 0904-7118; 49452-4718; 51927-2697; 50090-0489; 51407-109; 51655-527; 60760-524; 63187-314; 63323-660; 68788-7548; 70518-2024; 70518-3291; 70518-3606; 71335-2064; 71610-559; 0615-8017; 0615-8322; 82727-002; 42419-009; 52817-361; 55289-382 |
| UNII |
W5S57Y3A5L
|
| Synonyms |
Metoprolol | Toprol | Betaloc | Betaloc-Astra | Betaloc Astra | Betalok | CGP-2175 | CGP 2175 | CGP2175 | H 93-26 | H 93 26 | H 9326 | Metoprolol Tartrate | Seloken | Spesicor | Spesikor | Metoprolol Succinate | Metoprolol CR-XL | Metoprolol CR XL | Toprol-XL | Toprol XL | Beloc-Duriles | Beloc Duriles | Lopressor |
