Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Midodrine
Drug ID BADD_D01461
Description An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Indications and Usage For the treatment of symptomatic orthostatic hypotension (OH).
Marketing Status approved
ATC Code C01CA17
DrugBank ID DB00211
KEGG ID D08220
MeSH ID D008879
PubChem ID 4195
TTD Drug ID D02XJY
NDC Product Code Not Available
UNII 6YE7PBM15H
Synonyms Midodrine | Midodrin | Midodrine Hydrochloride | Midodrine Monohydrochloride | Monohydrochloride, Midodrine | ProAmatine | Amatine | ST-1085 | ST 1085 | ST1085 | Gutron | Midon
Chemical Information
Molecular Formula C12H18N2O4
CAS Registry Number 42794-76-3
SMILES COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Urinary tract disorder20.08.01.001--Not Available
Visual field defect17.17.01.001; 06.02.07.003--Not Available
Vomiting07.01.07.0030.002528%
Gaze palsy17.02.05.044; 06.05.02.0140.000648%Not Available
Vasodilation procedure25.03.01.001--Not Available
Angiopathy24.03.02.007--Not Available
Hepatic enzyme increased13.03.04.028--Not Available
Cardiac disorder02.11.01.003--Not Available
Mental disorder19.07.01.002--Not Available
Hepatobiliary disease09.01.08.003--Not Available
Drug-induced liver injury12.03.01.044; 09.01.07.0230.000648%Not Available
Hypertensive emergency24.08.01.0040.002268%Not Available
Stress cardiomyopathy24.04.04.026; 02.04.01.0120.000972%Not Available
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