| Pharmaceutical Information |
| Drug Name |
Mitotane |
| Drug ID |
BADD_D01479 |
| Description |
A derivative of the insecticide dichlorodiphenyldichloroethane that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression. |
| Indications and Usage |
For treatment of inoperable adrenocortical tumours; Cushing's syndrome |
| Marketing Status |
approved |
| ATC Code |
L01XX23 |
| DrugBank ID |
DB00648
|
| KEGG ID |
D00420
|
| MeSH ID |
D008939
|
| PubChem ID |
4211
|
| TTD Drug ID |
D0Z5OE
|
| NDC Product Code |
71052-048; 76336-080; 62991-2604; 14799-2009; 38779-2263; 21222-002; 49452-4786 |
| UNII |
78E4J5IB5J
|
| Synonyms |
Mitotane | o,p-DDD | Mytotan | ortho,para-DDD | ortho,para DDD | Chlodithane | Lysodren | Chloditan | Khloditan |
|
| Chemical Information |
| Molecular Formula |
C14H10Cl4 |
| CAS Registry Number |
53-19-0 |
| SMILES |
C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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