| Pharmaceutical Information |
| Drug Name |
Moclobemide |
| Drug ID |
BADD_D01483 |
| Description |
A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs). Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A3901]. |
| Indications and Usage |
For the treatment of major depressive disorder and bipolar disorder [A31901]. |
| Marketing Status |
approved; investigational |
| ATC Code |
N06AG02 |
| DrugBank ID |
DB01171
|
| KEGG ID |
D02561
|
| MeSH ID |
D020912
|
| PubChem ID |
4235
|
| TTD Drug ID |
D01ZSO
|
| NDC Product Code |
Not Available |
| UNII |
PJ0Y7AZB63
|
| Synonyms |
Moclobemide | Moclobamide | Apo-Moclobemide | Apo Moclobemide | Arima | Aurorix | Manerix | Moclamine | Aurorex | Chem mart Moclobemide | Moclobemide, Chem mart | DBL Moclobemide | Moclobemide, DBL | Deprenorm | Feraken | GenRX Moclobemide | Moclobemide, GenRX | Healthsense Moclobemide | Moclobemide, Healthsense | Moclix | Terry White Chemists Moclobemide | Moclobemid Stada | Stada, Moclobemid | Moclobemid von ct | von ct, Moclobemid | Moclobemid-1A Pharma | Moclobemid 1A Pharma | Moclobemid1A Pharma | Moclobemid-Puren | Moclobemid Puren | Moclobemid-ratiopharm | Moclobemid ratiopharm | Moclobeta | Moclodura | Moclonorm | Nu-Moclobemide | Nu Moclobemide | NuMoclobemide | PMS-Moclobemide | PMS Moclobemide | Rimoc | Ro 11-1163 | Ro 11 1163 | Ro-11-1163 | Novo-Moclobemide | Novo Moclobemide | NovoMoclobemide | Moclobemid AZU | AZU, Moclobemid |
|
| Chemical Information |
| Molecular Formula |
C13H17ClN2O2 |
| CAS Registry Number |
71320-77-9 |
| SMILES |
C1COCCN1CCNC(=O)C2=CC=C(C=C2)Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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