Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Moexiprilat
Drug ID BADD_D01486
Description The active metabolite of the prodrug [Moexipril].
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14210
KEGG ID Not Available
MeSH ID C059506
PubChem ID 55331
TTD Drug ID D0R6KV
NDC Product Code Not Available
UNII H3753190JS
Synonyms moexiprilat | 2-(2-(1-carboxy-3-phenylpropyl)amino-1-oxopropyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid | RS 10029 | RS-10029 | moexiprilat, (3S-(2(S*(R*)),3R*))-isomer | moexiprilat, (3R-(2(S*(S*)),3R*))-isomer | moexiprilat, (3S-(2(R*(S*)).3R*))-isomer
Chemical Information
Molecular Formula C25H30N2O7
CAS Registry Number 103775-14-0
SMILES CC(C(=O)N1CC2=CC(=C(C=C2CC1C(=O)O)OC)OC)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain02.02.02.011; 22.12.02.003; 08.01.08.002--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flushing23.06.05.003; 08.01.03.025; 24.03.01.002--
Gastrointestinal pain07.01.05.005--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
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