Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Moxifloxacin
Drug ID BADD_D01501
Description Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Indications and Usage For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).
Marketing Status approved; investigational
ATC Code J01MA14; S01AE07
DrugBank ID DB00218
KEGG ID D08237
MeSH ID D000077266
PubChem ID 152946
TTD Drug ID D0ZV0Z
NDC Product Code 65977-0038; 51407-321; 63629-8357; 0378-5430; 65862-840; 72189-321; 16714-643; 50090-6357; 55111-112; 70518-3713; 80425-0239; 50090-5833; 53002-2723; 68180-421; 61919-553; 72789-233; 60505-0582; 68180-422; 72189-334; 17478-519; 31722-845; 0904-6406; 12527-0517; 50090-3147
UNII U188XYD42P
Synonyms Moxifloxacin | 1-Cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | Octegra | Proflox | Moxifloxacin Hydrochloride | Avelox | Avalox | Izilox | Actira | BAY 12-8039 | BAY 12 8039 | BAY-12-8039 | BAY 128039 | BAY-128039 | BAY128039
Chemical Information
Molecular Formula C21H24FN3O4
CAS Registry Number 151096-09-2
SMILES COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tubulointerstitial nephritis20.05.02.002--Not Available
Mobility decreased17.02.05.018; 15.03.05.023; 08.01.03.030--Not Available
Joint range of motion decreased15.01.02.006--
Hypoacusis04.02.01.006--
Peripheral swelling08.01.03.053; 02.05.04.015--Not Available
Emotional distress19.04.02.008--Not Available
Balance disorder08.01.03.081; 17.02.02.007--Not Available
Musculoskeletal chest pain22.09.01.001; 15.03.04.012--
Deep vein thrombosis24.01.02.003--Not Available
Foreign body sensation in eyes06.01.01.0060.000431%Not Available
Platelet count increased13.01.04.002--Not Available
Conjunctival hyperaemia06.04.01.0040.000202%Not Available
Eyelids pruritus06.08.03.007; 23.03.12.0050.000135%Not Available
Ear pruritus04.03.01.011--Not Available
Eye oedema06.08.03.0130.000337%Not Available
Eye pruritus06.04.05.0060.000566%Not Available
Musculoskeletal stiffness15.03.05.027--Not Available
Infusion site phlebitis24.12.03.002; 12.07.05.004; 08.02.05.003--Not Available
Skin burning sensation23.03.03.021; 17.02.06.009--Not Available
Transaminases increased13.03.04.036--Not Available
Corneal neovascularisation24.03.07.009; 06.07.01.0030.000135%Not Available
Vulvovaginal pruritus21.08.02.004; 23.03.12.009--Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.003--Not Available
Paraesthesia oral17.02.06.008; 07.05.05.035--Not Available
Ocular icterus01.06.04.007; 09.01.01.007; 06.08.03.009--Not Available
Restless legs syndrome15.05.03.012; 17.02.07.008--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Drug resistance08.06.01.0050.000135%Not Available
Hepatic enzyme increased13.03.04.028--Not Available
Calcium ionised increased13.11.01.018--Not Available
The 10th Page    First    Pre   10 11    Next   Last    Total 11 Pages