Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Moxifloxacin
Drug ID BADD_D01501
Description Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Indications and Usage For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).
Marketing Status approved; investigational
ATC Code J01MA14; S01AE07
DrugBank ID DB00218
KEGG ID D08237
MeSH ID D000077266
PubChem ID 152946
TTD Drug ID D0ZV0Z
NDC Product Code 65977-0038; 51407-321; 63629-8357; 0378-5430; 65862-840; 72189-321; 16714-643; 50090-6357; 55111-112; 70518-3713; 80425-0239; 50090-5833; 53002-2723; 68180-421; 61919-553; 72789-233; 60505-0582; 68180-422; 72189-334; 17478-519; 31722-845; 0904-6406; 12527-0517; 50090-3147
UNII U188XYD42P
Synonyms Moxifloxacin | 1-Cyclopropyl--7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | Octegra | Proflox | Moxifloxacin Hydrochloride | Avelox | Avalox | Izilox | Actira | BAY 12-8039 | BAY 12 8039 | BAY-12-8039 | BAY 128039 | BAY-128039 | BAY128039
Chemical Information
Molecular Formula C21H24FN3O4
CAS Registry Number 151096-09-2
SMILES COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Adverse event08.06.01.010--Not Available
Cardiac disorder02.11.01.003--Not Available
Oral fungal infection11.03.05.010; 07.05.07.009--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Psychotic disorder19.03.01.002--
Immunosuppression10.03.02.001--Not Available
Hyperlipidaemia14.08.03.001--
Renal impairment20.01.03.010--Not Available
Increased upper airway secretion22.12.03.007--Not Available
Infusion site extravasation12.07.05.008; 08.02.05.007--
Vulvovaginal mycotic infection21.14.02.004; 11.03.05.004--Not Available
Ulcerative keratitis10.02.01.021; 06.04.02.0040.000808%
Ventricular tachyarrhythmia02.03.04.012--Not Available
Suicidal behaviour19.12.01.006--Not Available
Tendon pain15.07.01.009--Not Available
Oropharyngeal pain22.12.03.016; 07.05.05.004--
Acute kidney injury20.01.03.016--
Bilirubin conjugated decreased13.03.04.013--Not Available
Candida infection11.03.03.021--
Depersonalisation/derealisation disorder19.14.01.004--Not Available
Pharyngeal hypoaesthesia22.04.05.017; 17.02.06.034--Not Available
Anterior chamber disorder06.06.07.0020.000269%Not Available
Tongue discomfort07.14.02.019--Not Available
Hypersensitivity pneumonitis22.01.01.027; 10.01.03.056--Not Available
Iris transillumination defect06.06.06.0090.000431%Not Available
Pharyngeal swelling22.04.05.028--Not Available
Reaction to excipient10.01.01.0420.000135%Not Available
Sinus pain22.12.03.023--
Brain fog19.21.02.017; 17.02.05.077; 16.32.03.050--Not Available
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