Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Nadolol
Drug ID BADD_D01512
Description Nadolol is a nonselective beta adrenal receptor blocker that is used to lower blood pressure.[L7922,L7925] Nonselective beta adrenal receptor blockers may no longer be first line in the treatment of hypertension as newer generations of beta adrenal receptor blockers have higher selectivity and offer better rates of adverse effects.[A34177] Nadolol was granted FDA approval on 10 December 1979.[L7922]
Indications and Usage Nadolol is indicated to treat angina pectoris and hypertension.[L7922] Another product formulated with [bendroflumethiazide] is indicated to treat hypertension.[L7925]
Marketing Status approved
ATC Code C07AA12
DrugBank ID DB01203
KEGG ID D00432
MeSH ID D009248
PubChem ID 39147
TTD Drug ID D05SHK
NDC Product Code 0904-7071; 42973-148; 62332-402; 69238-1125; 70771-1089; 72664-213; 76282-348; 76385-134; 51927-2776; 23155-732; 59762-0812; 0378-0028; 67787-348; 71335-2131; 76282-347; 46708-404; 70518-2139; 71335-1972; 59651-589; 60687-302; 68001-317; 68001-319; 68382-734; 69097-868; 69238-1124; 72664-211; 0781-8005; 10135-687; 59651-251; 60687-313; 67787-349; 68382-733; 69097-867; 69238-1123; 72664-212; 78670-100; 78670-101; 12780-0154; 0904-7070; 23155-731; 76385-135; 0781-8004; 51927-0238; 10135-688; 65015-718; 51079-812; 62332-404; 0378-1132; 0378-1171; 68001-318; 68382-732; 71335-0697; 0781-8006; 46708-402; 59762-0810; 59762-0811; 62332-403; 67787-347; 70771-1090; 23155-730; 59651-252; 70518-1755; 70771-1091; 76282-349; 76385-133; 10135-686; 69575-4016; 69097-869; 46708-403
UNII FEN504330V
Synonyms Nadolol | SQ-11725 | SQ 11725 | SQ11725 | Corgard | Solgol
Chemical Information
Molecular Formula C17H27NO4
CAS Registry Number 1403-22-1
SMILES CC(C)(C)NCC(COC1=CC=CC2=C1CC(C(C2)O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.0020.000345%
Adams-Stokes syndrome17.02.04.010; 02.03.01.001--Not Available
Agitation19.06.02.001; 17.02.05.0120.000689%
Agitation neonatal18.04.04.002; 17.02.05.0280.000345%Not Available
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Amnesia19.20.01.001; 17.03.02.001--
Arrhythmia02.03.02.001--Not Available
Arterial thrombosis24.01.01.002--Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.0020.000345%
Atrioventricular block02.03.01.002--Not Available
Atrioventricular block complete02.03.01.003--
Atrioventricular block first degree02.03.01.004--
Atrioventricular block second degree02.03.01.0050.000345%
Back pain15.03.04.005--
Blood triglycerides increased13.12.03.001--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.0020.004308%Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.0010.002240%
Cardiac failure02.05.01.001--
Cardiac failure congestive02.05.01.002--Not Available
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.000345%Not Available
Cardiogenic shock24.06.02.006; 02.05.01.0030.001206%Not Available
Cardiomegaly02.04.02.001--Not Available
Catatonia19.11.01.001--Not Available
Chest pain02.02.02.011; 22.12.02.003; 08.01.08.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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