| Pharmaceutical Information |
| Drug Name |
Nafcillin |
| Drug ID |
BADD_D01515 |
| Description |
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360]. |
| Indications and Usage |
Indicated in the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug. |
| Marketing Status |
approved; investigational |
| ATC Code |
J01CF06 |
| DrugBank ID |
DB00607
|
| KEGG ID |
D08242
|
| MeSH ID |
D009254
|
| PubChem ID |
8982
|
| TTD Drug ID |
D0A0JH
|
| NDC Product Code |
44567-223; 0338-1019; 44567-221; 63323-330; 0338-1017; 44567-222 |
| UNII |
4CNZ27M7RV
|
| Synonyms |
Nafcillin | Naphthamidopenicillin | Nafcil | Nafcillin Sodium | Sodium, Nafcillin | Nafcillin, Monosodium Salt, Anhydrous | Sodium Nafcillin | Nafcillin, Sodium |
|
| Chemical Information |
| Molecular Formula |
C21H22N2O5S |
| CAS Registry Number |
147-52-4 |
| SMILES |
CCOC1=C(C2=CC=CC=C2C=C1)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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