Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Naftifine hydrochloride
Drug ID BADD_D01518
Description Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Indications and Usage For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Marketing Status approved
ATC Code D01AE22
DrugBank ID DB00735
KEGG ID D00883
MeSH ID C029178
PubChem ID 5281098
TTD Drug ID D00HPK
NDC Product Code 51672-1362; 54766-772; 70700-161; 14501-0001; 54766-770; 0115-1510; 51672-1368; 17337-0531; 0115-1512; 51672-1376; 49706-0915
UNII 25UR9N9041
Synonyms naftifine | naftifin | naftifine hydrochloride, (E)-isomer | naftifine hydrochloride | N-cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride
Chemical Information
Molecular Formula C21H22ClN
CAS Registry Number 65473-14-5
SMILES CN(CC=CC1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001--Not Available
Blister23.03.01.001; 12.01.06.002--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Erythema23.03.06.001--Not Available
Headache17.14.01.001--
Leukopenia01.02.02.001--Not Available
Pruritus23.03.12.001--
Scab23.03.03.004--Not Available
Skin irritation23.03.04.009--Not Available
Swelling08.01.03.015--Not Available
Skin maceration23.03.03.016--Not Available
Bloody discharge24.07.01.041; 08.01.03.039--Not Available
Inflammation10.02.01.089; 08.01.05.007--Not Available
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