Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nalbuphine
Drug ID BADD_D01519
Description A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status approved
ATC Code N02AF02
DrugBank ID DB00844
KEGG ID D08246
MeSH ID D009266
PubChem ID 5311304
TTD Drug ID D01KQA
NDC Product Code Not Available
UNII L2T84IQI2K
Synonyms Nalbuphine | Nalbuphine Hydrochloride | Nalbuphine Serb | EN-2234A | EN 2234A | EN2234A | Nubain
Chemical Information
Molecular Formula C21H27NO4
CAS Registry Number 20594-83-6
SMILES C1CC(C1)CN2CCC34C5C(CCC3(C2CC6=C4C(=C(C=C6)O)O5)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Foetal death08.04.01.011; 18.01.02.003--
Depersonalisation/derealisation disorder19.14.01.004--Not Available
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