Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nandrolone decanoate
Drug ID BADD_D01530
Description Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid indicated in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis.[A233789,A233849,L32564,L9464] The process for creating esters of [nandrolone] was patented in Spain in 1959[L33244] and in 1960, it was described as having a long duration of action and strong anabolic effect compared to nandrolone and other esters.[A233849] Nandrolone decanoate was granted FDA approval on 5 October 1962.[L32564]
Indications and Usage For the treatment of refractory deficient red cell production anemias, breast carcinoma, hereditary angioedema, antithrombin III deficiency, fibrinogen excess, growth failure and Turner's syndrome. It is also indicated in the prophylaxis of hereditary angioedema.
Marketing Status Prescription; Discontinued
ATC Code A14AB01; S01XA11
DrugBank ID DB08804
KEGG ID D00955
MeSH ID D000077603
PubChem ID 9677
TTD Drug ID Not Available
NDC Product Code 51927-0121; 51552-1564; 60870-0233; 62991-2186; 43647-123; 22552-0048; 10695-051; 63275-9889
Synonyms Nandrolone Decanoate | 17 beta-Hydroxyestr-4-en-3-one 17-decanoate | 17 beta Hydroxyestr 4 en 3 one 17 decanoate | 19-Nortestosterone Decanoate | 19 Nortestosterone Decanoate | 19-nor-4-Androstene-17 beta-ol-3-one 17-decanoate | 19 nor 4 Androstene 17 beta ol 3 one 17 decanoate | Retabolil | Retabolyl | Decadurabolin | Decadurobolin
Chemical Information
Molecular Formula C28H44O3
CAS Registry Number 360-70-3
SMILES CCCCCCCCCC(=O)OC1CCC2C1(CCC3C2CCC4=CC(=O)CCC34)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Amenorrhoea21.01.02.001; 05.05.01.002--
Azoospermia21.03.03.001--
Benign prostatic hyperplasia21.04.02.001--Not Available
Bladder irritation20.02.02.020--Not Available
Blood calcium increased13.11.01.003--Not Available
Blood chloride increased13.11.01.005--Not Available
Blood creatine increased13.13.01.001--Not Available
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine increased13.13.01.004--
Blood potassium increased13.11.01.011--Not Available
Clitoral engorgement21.08.02.006--Not Available
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.004--
Electrolyte imbalance14.05.01.002--Not Available
Epididymitis21.09.02.001; 11.01.19.005--Not Available
Epiphyses premature fusion15.02.02.001; 05.05.03.002--Not Available
Erection increased21.03.01.004; 19.08.04.002--Not Available
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Furuncle23.09.01.004; 11.02.05.008--Not Available
Glucose tolerance decreased13.02.02.004--Not Available
Gynaecomastia05.05.02.003; 21.05.04.003--
Haemoglobin increased13.01.05.004--
Hepatic function abnormal09.01.02.001--Not Available
Hepatic neoplasm16.07.03.001; 09.04.03.001--Not Available
High density lipoprotein decreased13.12.01.003--Not Available
Hirsutism23.02.04.001; 05.05.01.005--
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