Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Naphazoline hydrochloride
Drug ID BADD_D01532
Description Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609].
Indications and Usage Naphazoline is indicated for use as OTC eyedrops for ocular vasoconstriction or as a nasal preparation for nasal congestion[A176558,L5804,L5807].
Marketing Status approved; investigational
ATC Code R01AA08; S01GA01; R01AB02
DrugBank ID DB06711
KEGG ID D00743
MeSH ID D009278
PubChem ID 11079
TTD Drug ID D0O6IZ
NDC Product Code 62668-6900; 49873-057; 51367-035; 73435-014; 42571-310; 49452-4810; 49873-044
UNII MZ1131787D
Synonyms Naphazoline | AK-Con | AK Con | Albalon | All Clear | Clear Eyes | Colirio Alfa | Idril | Miraclar | Nafazair | Naphazoline Hydrochloride | Hydrochloride, Naphazoline | Naphazoline Monohydrochloride | Monohydrochloride, Naphazoline | Naphazoline Nitrate | Nitrate, Naphazoline | Naphcon | Naphcon Forte | Optazine | Privine | Privin | Proculin | Siozwo | Tele-Stulln | Tele Stulln | Vasoclear | Vasocon | Vasocon Regular | Vasoconstrictor Pensa | Pensa, Vasoconstrictor | VasoNit | Afazol Grin
Chemical Information
Molecular Formula C14H15ClN2
CAS Registry Number 550-99-2
SMILES C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Asthenia08.01.01.001--Not Available
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.11.04.006--
Headache17.14.01.001--
Heart rate irregular13.14.04.003--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.001--
Intraocular pressure increased13.07.04.002--Not Available
Lacrimation increased06.08.02.004--
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Ocular hyperaemia06.04.05.004--Not Available
Punctate keratitis06.04.02.003--Not Available
Skin irritation23.03.04.009--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Vision blurred17.17.01.010; 06.02.06.007--
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