Drug Name |
Nebivolol hydrochloride |
Drug ID |
BADD_D01542 |
Description |
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity.[A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol].[A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are first treated with thiazide diuretics.[A182594]
Nebivolol was granted FDA approval on 17 December 2007.[L7985] |
Indications and Usage |
Nebivolol is indicated to treat hypertension.[A2762,A182579,L7985,L7988] |
Marketing Status |
approved; investigational |
ATC Code |
C07AB12 |
DrugBank ID |
DB04861
|
KEGG ID |
D06622
|
MeSH ID |
D000068577
|
PubChem ID |
9933004
|
TTD Drug ID |
D0Z1UA
|
NDC Product Code |
29300-377; 0456-1402; 0456-1420; 0456-1411; 0456-1421; 50370-0012; 66577-024; 29300-378; 50090-1127; 50090-3326; 65691-0062; 69037-0004; 76397-009; 0456-1410; 64220-187; 76397-008; 29300-375; 29300-376; 68462-617; 0456-1403; 0456-1406; 52133-0039; 50090-1307; 68462-618; 68462-615; 68462-616; 0456-1405 |
UNII |
JGS34J7L9I
|
Synonyms |
Nebivolol | Alpha,Alpha'-(Iminobis(Methylene))bis(6-Fluoro-3,4-dihydro)-2H-1-benzopyran-2-methanol | Bystolic | Nebilet | Silostar | Nebivolol Hydrochloride | Hydrochloride, Nebivolol | R 67555 | 67555, R | R-67555 | R67555 | Lobivon |