Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nedocromil
Drug ID BADD_D01544
Description A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Indications and Usage For the treatment of mild to moderate asthma
Marketing Status approved; investigational
ATC Code R01AC07; R03BC03; S01GX04
DrugBank ID DB00716
KEGG ID D05129
MeSH ID D017835
PubChem ID 50294
TTD Drug ID D06FVX
NDC Product Code Not Available
UNII 0B535E0BN0
Synonyms Nedocromil | 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid | Alocril | Brionil | Nedocromil, Disodium salt, Hydrate | FPL-59002 | FPL 59002 | FPL59002 | Halamid | Nedocromil Calcium | Calcium, Nedocromil | Nedocromil, Calcium Salt (1:1) | Nedocromil Sodium | Sodium, Nedocromil | Nedocromil, Disodium Salt | Tilade | Irtan | Tilaire | Rapitil | Tilad | Tilavist | Cetimil
Chemical Information
Molecular Formula C19H17NO7
CAS Registry Number 69049-73-6
SMILES CCCC1=C2C(=CC3=C1OC(=CC3=O)C(=O)O)C(=O)C=C(N2CC)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Ocular hyperaemia06.04.05.004--Not Available
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Photophobia17.17.02.006; 06.01.01.004--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pulmonary eosinophilia22.01.01.009; 01.02.04.006--Not Available
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Sinusitis22.07.03.007; 11.01.13.005--
Sputum increased22.02.03.007--Not Available
Tremor17.01.06.002--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urticaria10.01.06.001; 23.04.02.001--
Viral infection11.05.04.001--Not Available
Visual impairment06.02.10.013--Not Available
Vomiting07.01.07.003--
Increased bronchial secretion22.12.01.002--Not Available
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