Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nedocromil sodium
Drug ID BADD_D01545
Description A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Indications and Usage For the treatment of mild to moderate asthma
Marketing Status approved; investigational
ATC Code S01GX04; R01AC07; R03BC03
DrugBank ID DB00716
KEGG ID D00527
MeSH ID D017835
PubChem ID 50295
TTD Drug ID D06FVX
NDC Product Code 82298-911; 0023-8842; 62255-1323
UNII ET8IF4KS1T
Synonyms Nedocromil | 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid | Alocril | Brionil | Nedocromil, Disodium salt, Hydrate | FPL-59002 | FPL 59002 | FPL59002 | Halamid | Nedocromil Calcium | Calcium, Nedocromil | Nedocromil, Calcium Salt (1:1) | Nedocromil Sodium | Sodium, Nedocromil | Nedocromil, Disodium Salt | Tilade | Irtan | Tilaire | Rapitil | Tilad | Tilavist | Cetimil
Chemical Information
Molecular Formula C19H15NNa2O7
CAS Registry Number 69049-74-7
SMILES CCCC1=C2C(=CC3=C1OC(=CC3=O)C(=O)[O-])C(=O)C=C(N2CC)C(=O)[O-].[Na+].[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Application site irritation08.02.01.003; 12.07.01.003--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Conjunctivitis11.01.06.012; 06.04.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Eye irritation06.04.05.003--Not Available
Headache17.14.01.001--
Nasal congestion22.04.04.001--
Ocular hyperaemia06.04.05.004--Not Available
Pain08.01.08.004--
Photophobia17.17.02.006; 06.01.01.004--
Rhinitis22.07.03.006; 11.01.13.004--
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