Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Nefopam
Drug ID BADD_D01548
Description Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
Indications and Usage Not Available
Marketing Status approved; investigational
ATC Code N02BG06
DrugBank ID DB12293
KEGG ID D08258
MeSH ID D009340
PubChem ID 4450
TTD Drug ID D05AFX
NDC Product Code Not Available
UNII 4UP8060B7J
Synonyms Nefopam | Nefopam Hydrochloride | Hydrochloride, Nefopam | Fenazoxine | Acupan | Ajan | Silentan Nefopam | Nefopam, Silentan
Chemical Information
Molecular Formula C17H19NO
CAS Registry Number 13669-70-0
SMILES CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Angina pectoris24.04.04.002; 02.02.02.002--
Confusional state19.13.01.001; 17.02.03.005--
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Dry mouth07.06.01.002--
Erythema multiforme23.03.01.003; 10.01.03.015--
Feeling abnormal08.01.09.014--Not Available
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Insomnia19.02.01.002; 17.15.03.002--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Urinary retention20.02.02.011--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
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