| Pharmaceutical Information |
| Drug Name |
Nesiritide |
| Drug ID |
BADD_D01556 |
| Description |
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. |
| Indications and Usage |
For the intravenous treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity. |
| Marketing Status |
approved; investigational |
| ATC Code |
C01DX19 |
| DrugBank ID |
DB04899
|
| KEGG ID |
D05147
|
| MeSH ID |
D020097
|
| PubChem ID |
53325981
|
| TTD Drug ID |
D05GRY
|
| NDC Product Code |
35207-0009 |
| UNII |
P7WI8UL647
|
| Synonyms |
Natriuretic Peptide, Brain | Peptide, Brain Natriuretic | BNP-32 | BNP 32 | Brain Natriuretic Peptide-32 | Brain Natriuretic Peptide 32 | Natriuretic Peptide-32, Brain | Peptide-32, Brain Natriuretic | Natriuretic Factor-32 | Natriuretic Factor 32 | BNP Gene Product | Type-B Natriuretic Peptide | Natriuretic Peptide, Type-B | Type B Natriuretic Peptide | Natriuretic Peptide Type-B | Natriuretic Peptide Type B | Nesiritide | Brain Natriuretic Peptide | B-Type Natriuretic Peptide | Natriuretic Peptide, B-Type | Ventricular Natriuretic Peptide, B-type | Ventricular Natriuretic Peptide, B type | Natrecor |
|
| Chemical Information |
| Molecular Formula |
C143H244N50O42S4 |
| CAS Registry Number |
124584-08-3 |
| SMILES |
CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O
)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCNC(=N)N)CC(=O)O)CC
SC)CCCCN)CCCNC(=N)N)CC2=CC=CC=C2)NC(=O)CNC(=O)C(CO)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O
)C(C(C)C)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C3CCCN3C(=O)C(CO)N)C(=O)NC(CCCCN)C(=O)
NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC4=CN=CN4
)C(=O)O)CC(C)C)CO)CO)CO)CO |
| Chemical Structure |
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| ADRs Induced by Drug |
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