Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Norfloxacin
Drug ID BADD_D01587
Description A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Indications and Usage For the treatment of urinary tract infection
Marketing Status approved
ATC Code J01MA06; S01AE02
DrugBank ID DB01059
KEGG ID D00210
MeSH ID D009643
PubChem ID 4539
TTD Drug ID D0Q2PE
NDC Product Code 53104-7517
UNII N0F8P22L1P
Synonyms Norfloxacin | MK-0366 | MK 0366 | MK-366 | MK 366 | MK0366 | MK366 | Noroxin | AM-0715 | AM 0715 | AM0715 | AM-715 | AM 715
Chemical Information
Molecular Formula C16H18FN3O3
CAS Registry Number 70458-96-7
SMILES CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Erythema multiforme23.03.01.003; 10.01.03.015--
Euphoric mood19.04.02.006--
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Flushing08.01.03.025; 24.03.01.002; 23.06.05.003--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Gingival swelling07.09.13.013--Not Available
Glucose-6-phosphate dehydrogenase deficiency14.14.03.001; 03.08.03.001; 01.06.05.001--Not Available
Glycosuria20.02.01.005--
Guillain-Barre syndrome17.09.01.001; 11.07.01.001; 10.04.10.005--
Haematocrit decreased13.01.05.001--Not Available
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Haemoglobin decreased13.01.05.003--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatic necrosis09.01.07.002--
Hepatitis09.01.07.004--Not Available
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Hypersensitivity vasculitis24.12.04.013; 23.06.02.005; 10.02.02.017; 01.01.04.008--Not Available
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypoaesthesia17.02.06.023; 23.03.03.081--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.001--
Insomnia19.02.01.002; 17.15.03.002--
Intermittent explosive disorder19.18.01.006--Not Available
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