| Pharmaceutical Information |
| Drug Name |
Omega-3-carboxylic acids |
| Drug ID |
BADD_D01612 |
| Description |
The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl esters. It is a complex mixture of the free fatty acids form containing eicosapentaenoic acid and docosahexaenoic acid as the most abundant species found in a proportion of 55% and 20% respectively. The rest of the concentration is represented by docosapentaenoic acid and traces of some other components such as alpha-tocopherol, gelatin, glycerol, sorbitol and purified water.[A25808] It was developed by AstraZeneca Pharmaceuticals and firstly approved by the FDA on May 05, 2014.[L2386] |
| Indications and Usage |
OM3-CA is indicated as an adjunct to diet to reduce triglycerides levels in adults patients with severe hypertriglyceridemia (>500 mg/dL). The patients involved in this treatment should be laced with an appropriate lipid-lowering diet.[L2387]
Hypertriglyceridemia is defined as an elevated plasma triglyceride concentration. It is usually correlated to other secondary conditions such as poor diet, alcohol use, obesity, metabolic syndrome and type 2 diabetes.[A32630] |
| Marketing Status |
approved; investigational |
| ATC Code |
Not Available |
| DrugBank ID |
DB09568
|
| KEGG ID |
Not Available
|
| MeSH ID |
D002264
|
| PubChem ID |
446284
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
Not Available |
| UNII |
F85N2YHE4E
|
| Synonyms |
Carboxylic Acids | Acids, Carboxylic | Carboxylic Acid | Acid, Carboxylic |
|
| Chemical Information |
| Molecular Formula |
C20H30O2 |
| CAS Registry Number |
10417-94-4 |
| SMILES |
CCC=CCC=CCC=CCC=CCC=CCCCC(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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