Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxytetracycline hydrochloride
Drug ID BADD_D01651
Description A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Indications and Usage Oxytetracycline is indicated for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.
Marketing Status approved; investigational; vet_approved
ATC Code D06AA03; J01AA06; S01AA04; G01AA07; A01AB25
DrugBank ID DB00595
KEGG ID D01596
MeSH ID D010118
PubChem ID 54680782
TTD Drug ID D0J2NK
NDC Product Code 24507-003; 71057-0100; 54509-0002; 51671-0003; 82403-002
UNII 4U7K4N52ZM
Synonyms Oxytetracycline | Hydroxytetracycline | Geomycin | Oxyterracin | Oxyterracine | Oxytetracid | Oxytetracycline Calcium | Oxytetracycline Dihydrate | Oxytetracycline Hydrochloride | Oxytetracycline Monohydrochloride | Oxytetracycline Sulfate (2:1) | Oxytetracycline, (4a beta,5 beta,5a beta,12a beta)-Isomer | Oxytetracycline, (5 beta)-Isomer | Oxytetracycline, Anhydrous | Oxytetracycline Anhydrous | Oxytetracycline, Calcium (1:1) Salt | Oxytetracycline, Disodium Salt, Dihydrate | Oxytetracycline, Sodium Salt | Terramycin | Bisolvomycin
Chemical Information
Molecular Formula C22H24N2O9.ClH
CAS Registry Number 2058-46-0
SMILES CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Blood urea increased13.13.01.006--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Diarrhoea07.02.01.001--
Dysphagia07.01.06.003--
Enterocolitis07.08.03.003--
Eosinophilia01.02.04.001--
Fontanelle bulging18.04.04.001; 17.02.05.006--Not Available
Glossitis07.14.01.001--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Henoch-Schonlein purpura24.07.06.003; 23.06.01.002; 10.02.02.004; 01.01.04.001--Not Available
Nausea07.01.07.001--
Neutropenia01.02.03.004--Not Available
Oesophageal ulcer07.04.05.002--
Oesophagitis07.08.05.001--
Pericarditis02.06.02.001--
Rash erythematous23.03.13.029--Not Available
Rash maculo-papular23.03.13.004--
Systemic lupus erythematosus23.03.02.006; 15.06.02.003; 10.04.03.004--Not Available
Thrombocytopenia01.08.01.002--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
Inflammation10.02.01.089; 08.01.05.007--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Candida infection11.03.03.021--
Idiopathic intracranial hypertension17.07.02.011--Not Available
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