Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pancuronium bromide
Drug ID BADD_D01665
Description A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Indications and Usage Used as a muscle relaxant during anesthesia and surgical procedures.
Marketing Status approved
ATC Code M03AC01
DrugBank ID DB01337
KEGG ID D00492
MeSH ID D010197
PubChem ID 27350
TTD Drug ID D0AA0L
NDC Product Code 0409-4646; 55486-1568; 53183-0875
UNII U9LY9Y75X2
Synonyms Pancuronium | Pavulon | Pancuronium Organon | Pancuronium Bromide | Bromide, Pancuronium | Pancuronium Curamed
Chemical Information
Molecular Formula C35H60Br2N2O4
CAS Registry Number 15500-66-0
SMILES CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[B r-].[Br-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Apnoea22.02.01.001--
Bronchospasm22.03.01.004; 10.01.03.012--
Dermatitis23.03.04.002--Not Available
Drug interaction08.06.03.001--Not Available
Erythema23.03.06.001--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Light anaesthesia25.01.03.003--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Paralysis17.01.04.004--Not Available
Rash23.03.13.001--Not Available
Respiratory failure22.02.06.002; 14.01.04.003--
Salivary hypersecretion07.06.01.009--Not Available
Tachycardia02.03.02.007--Not Available
Pre-existing disease08.01.03.059--Not Available
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