| Pharmaceutical Information |
| Drug Name |
Papaverine hydrochloride |
| Drug ID |
BADD_D01671 |
| Description |
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. |
| Indications and Usage |
For the treatment of impotence and vasospasms. |
| Marketing Status |
approved; investigational |
| ATC Code |
G04BE02; A03AD01 |
| DrugBank ID |
DB01113
|
| KEGG ID |
D02218
|
| MeSH ID |
D010208
|
| PubChem ID |
6084
|
| TTD Drug ID |
D0NJ3V
|
| NDC Product Code |
51927-0223; 51927-1775; 43235-0009; 62991-1203; 72516-024; 0517-4002; 49452-5000; 76003-0850; 14789-121; 38779-0454; 54288-142 |
| UNII |
23473EC6BQ
|
| Synonyms |
Papaverine | Pavatym | Pavabid | Cerespan | Papaverine Hydrochloride | Hydrochloride, Papaverine |
|
| Chemical Information |
| Molecular Formula |
C20H21NO4.ClH |
| CAS Registry Number |
61-25-6 |
| SMILES |
COC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OC)OC)OC.Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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