| Pharmaceutical Information |
| Drug Name |
Pazopanib hydrochloride |
| Drug ID |
BADD_D01688 |
| Description |
Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009. |
| Indications and Usage |
Treatment of advanced renal cell cancer and advanced soft tissue sarcoma (in patients previously treated with chemotherapy) |
| Marketing Status |
approved |
| ATC Code |
L01EX03 |
| DrugBank ID |
DB06589
|
| KEGG ID |
D05380
|
| MeSH ID |
C516667
|
| PubChem ID |
11525740
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
68578-0015; 53104-7727; 0078-1077; 16436-0125; 63379-093; 54893-0014; 52482-015; 53296-0125; 62207-977; 68554-0058; 0078-0670; 76055-0050; 66499-0055 |
| UNII |
33Y9ANM545
|
| Synonyms |
pazopanib | GW 786034B | GW786034B | GW-786034B | GW 780604 | GW780604 | GW-780604 | Votrient |
|
| Chemical Information |
| Molecular Formula |
C21H24ClN7O2S |
| CAS Registry Number |
635702-64-6 |
| SMILES |
CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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