Pharmaceutical Information |
Drug Name |
Peginesatide |
Drug ID |
BADD_D01694 |
Description |
Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. Peginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine. FDA approved March 27, 2012. |
Indications and Usage |
Peginesatide is used for the treatment of anemia due to chronic kidney disease (CKD) in adult patients on dialysis |
Marketing Status |
approved; investigational |
ATC Code |
B03XA04 |
DrugBank ID |
DB08894
|
KEGG ID |
D09946
|
MeSH ID |
C556270
|
PubChem ID |
Not Available
|
TTD Drug ID |
Not Available
|
NDC Product Code |
Not Available |
UNII |
JX56W9N61Q
|
Synonyms |
peginesatide | AF-37702 | AF 37702 |
|
Chemical Information |
Molecular Formula |
Not Available |
CAS Registry Number |
913976-27-9 |
SMILES |
Not Available |
Chemical Structure |
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ADRs Induced by Drug |
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