Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Penciclovir
Drug ID BADD_D01708
Description Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Indications and Usage Used to treat recurrent cold sores on the lips and face from various herpesvirus invections.
Marketing Status approved
ATC Code D06BB06; J05AB13
DrugBank ID DB00299
KEGG ID D05407
MeSH ID C053539
PubChem ID 135398748
TTD Drug ID D07BYK
NDC Product Code 70600-022; 0378-0896; 29902-0021; 67835-0010; 69875-8004; 0378-9720; 63310-2500; 0093-3186; 65015-899; 71052-107
UNII 359HUE8FJC
Synonyms penciclovir | 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine | penciclovir, monosodium salt | BRL 39123 | BRL-39123 | Penciclovir Visfarm | Denavir | Vectavir | penciclovir, monosodium salt, monohydrate
Chemical Information
Molecular Formula C10H15N5O3
CAS Registry Number 39809-25-1
SMILES C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaemia01.03.02.001--
Anaesthesia17.02.06.036--Not Available
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Application site reaction12.07.01.006; 08.02.01.006--Not Available
Asthenia08.01.01.001--Not Available
Condition aggravated08.01.03.004--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Delirium19.13.02.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dysgeusia17.02.07.003; 07.14.03.001--
Dysmenorrhoea21.01.01.002--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Gastrointestinal pain07.01.05.005--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Hypersensitivity vasculitis24.12.04.013; 23.06.02.005; 10.02.02.017; 01.01.04.008--Not Available
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukopenia01.02.02.001--Not Available
Liver function test abnormal13.03.04.030--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
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