Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pentobarbital
Drug ID BADD_D01726
Description A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
Indications and Usage For the short-term treatment of insomnia.
Marketing Status approved; investigational; vet_approved
ATC Code N05CA01
DrugBank ID DB00312
KEGG ID D00499
MeSH ID D010424
PubChem ID 4737
TTD Drug ID D0F0YZ
NDC Product Code Not Available
UNII I4744080IR
Synonyms Pentobarbital | Pentobarbitone | Mebubarbital | Etaminal | Ethaminal | Sagatal | Nembutal | Pentobarbital Sodium | Pentobarbital, Monosodium Salt | Monosodium Salt Pentobarbital | Diabutal | Mebumal
Chemical Information
Molecular Formula C11H18N2O3
CAS Registry Number 57-33-0
SMILES CCCC(C)C1(C(=O)NC(=O)NC1=O)CC
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nightmare19.02.03.003--Not Available
Petechiae23.06.01.003; 24.07.06.004; 01.01.03.002--Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Rash23.03.13.001--Not Available
Rash macular23.03.13.003--Not Available
Rash maculo-papular23.03.13.004--
Respiratory failure14.01.04.003; 22.02.06.002--
Shock24.06.02.002--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Suicide attempt19.12.01.004--
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tension19.06.02.005--Not Available
Vasculitis10.02.02.006; 24.12.04.027--
Vomiting07.01.07.003--
Decreased appetite14.03.01.005; 08.01.09.028--
Liver injury12.01.17.012; 09.01.07.022--Not Available
The 2th Page    First    Pre   2    Total 2 Pages