Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Perhexiline
Drug ID BADD_D01737
Description Perhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Indications and Usage For the management of severe angina pectoris.
Marketing Status approved; investigational
ATC Code C08EX02
DrugBank ID DB01074
KEGG ID D08340
MeSH ID D010480
PubChem ID 4746
TTD Drug ID D00SBN
NDC Product Code Not Available
UNII KU65374X44
Synonyms Perhexiline | Perhexilene
Chemical Information
Molecular Formula C19H35N
CAS Registry Number 39648-47-0
SMILES C1CCC(CC1)C(CC2CCCCN2)C3CCCCC3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Blood triglycerides increased13.12.03.001--Not Available
Cachexia16.32.03.011; 14.03.02.001; 08.01.01.009--Not Available
Dermatitis23.03.04.002--Not Available
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Extrapyramidal disorder17.01.02.007--
Fatigue08.01.01.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gait disturbance15.03.05.013; 17.02.05.016; 08.01.02.002--
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hepatitis viral09.01.09.007; 11.05.04.011--
Hepatocellular injury09.01.07.008--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertriglyceridaemia14.08.02.001--
Hypoglycaemia14.06.03.001; 05.06.03.001--
Insomnia19.02.01.002; 17.15.03.002--
Loss of consciousness17.02.04.004--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Optic neuritis06.04.08.002; 10.02.01.097; 17.04.05.001--Not Available
Papilloedema24.03.07.001; 17.07.02.004; 06.09.02.002--
Paraesthesia23.03.03.094; 17.02.06.005--
Polyneuropathy17.09.03.012--Not Available
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