Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Piperacillin
Drug ID BADD_D01779
Description Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Indications and Usage For the treatment of polymicrobial infections.
Marketing Status approved
ATC Code J01CA12
DrugBank ID DB00319
KEGG ID D02251; D08380
MeSH ID D010878
PubChem ID 43672
TTD Drug ID D04ZAH
NDC Product Code 72977-0002; 65862-277; 50915-118; 66721-300
UNII X00B0D5O0E
Synonyms Piperacillin | Pipercillin | Piperacillin Sodium | Sodium, Piperacillin | Piperacillin Monosodium Salt | Monosodium Salt, Piperacillin | Salt, Piperacillin Monosodium | Pipracil | Pipril | T1220 | T-1220 | T 1220 | Piperacillin-Ratiopharm | Piperacillin Ratiopharm | Pipera-Hameln | Pipera Hameln | AB-Piperacillin | AB Piperacillin | Piperacillin Curasan | Curasan, Piperacillin | Piperacillin Fresenius | Piperacillin Hexal | Cl-227193 | Cl 227193 | Cl227193 | Pipcil
Chemical Information
Molecular Formula C23H27N5O7S
CAS Registry Number 61477-96-1
SMILES CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Activated partial thromboplastin time prolonged13.01.02.001--
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.04.005--
Anaemia01.03.02.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001--Not Available
Bleeding time prolonged13.01.02.002--Not Available
Blood albumin decreased13.09.01.001--Not Available
Blood bilirubin increased13.03.04.018--
Blood creatinine increased13.13.01.004--
Blood glucose decreased13.02.02.001--Not Available
Blood potassium decreased13.11.01.010--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Chills15.05.03.016; 08.01.09.001--
Constipation07.02.02.001--
Coombs direct test positive13.01.01.001--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Diarrhoea07.02.01.001--
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.002--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Drug interaction08.06.03.001--Not Available
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
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ADReCS-Target
Drug Name ADR Term Target
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