Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Piperacillin
Drug ID BADD_D01779
Description Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Indications and Usage For the treatment of polymicrobial infections.
Marketing Status approved
ATC Code J01CA12
DrugBank ID DB00319
KEGG ID D02251; D08380
MeSH ID D010878
PubChem ID 43672
TTD Drug ID D04ZAH
NDC Product Code 72977-0002; 65862-277; 50915-118; 66721-300
UNII X00B0D5O0E
Synonyms Piperacillin | Pipercillin | Piperacillin Sodium | Sodium, Piperacillin | Piperacillin Monosodium Salt | Monosodium Salt, Piperacillin | Salt, Piperacillin Monosodium | Pipracil | Pipril | T1220 | T-1220 | T 1220 | Piperacillin-Ratiopharm | Piperacillin Ratiopharm | Pipera-Hameln | Pipera Hameln | AB-Piperacillin | AB Piperacillin | Piperacillin Curasan | Curasan, Piperacillin | Piperacillin Fresenius | Piperacillin Hexal | Cl-227193 | Cl 227193 | Cl227193 | Pipcil
Chemical Information
Molecular Formula C23H27N5O7S
CAS Registry Number 61477-96-1
SMILES CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Eczema23.03.04.006--
Eosinophilia01.02.04.001--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.001--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gamma-glutamyltransferase increased13.03.04.024--
Gastrointestinal pain07.01.05.005--
Haematoma24.07.01.001--
Haemoglobin13.01.05.018--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hepatitis cholestatic09.01.01.002--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.003--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypokalaemia14.05.03.002--
Hypotension24.06.03.002--
Hypotonia17.05.02.002; 15.05.04.008--Not Available
Immune system disorder10.02.01.001--Not Available
Injection site reaction12.07.03.015; 08.02.03.014--
Insomnia19.02.01.002; 17.15.03.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Leukopenia01.02.02.001--Not Available
Liver disorder09.01.08.001--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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