Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Piperacillin
Drug ID BADD_D01779
Description Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Indications and Usage For the treatment of polymicrobial infections.
Marketing Status approved
ATC Code J01CA12
DrugBank ID DB00319
KEGG ID D02251; D08380
MeSH ID D010878
PubChem ID 43672
TTD Drug ID D04ZAH
NDC Product Code 72977-0002; 65862-277; 50915-118; 66721-300
UNII X00B0D5O0E
Synonyms Piperacillin | Pipercillin | Piperacillin Sodium | Sodium, Piperacillin | Piperacillin Monosodium Salt | Monosodium Salt, Piperacillin | Salt, Piperacillin Monosodium | Pipracil | Pipril | T1220 | T-1220 | T 1220 | Piperacillin-Ratiopharm | Piperacillin Ratiopharm | Pipera-Hameln | Pipera Hameln | AB-Piperacillin | AB Piperacillin | Piperacillin Curasan | Curasan, Piperacillin | Piperacillin Fresenius | Piperacillin Hexal | Cl-227193 | Cl 227193 | Cl227193 | Pipcil
Chemical Information
Molecular Formula C23H27N5O7S
CAS Registry Number 61477-96-1
SMILES CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Local reaction08.01.03.012--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Neutropenia01.02.03.004--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain08.01.08.004--
Pancytopenia01.03.03.003--Not Available
Phlebitis12.02.01.002; 24.12.03.004--
Prothrombin level increased13.01.02.011--Not Available
Pruritus23.03.12.001--
Pseudomembranous colitis11.02.02.002; 07.19.01.003--Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Stevens-Johnson syndrome12.03.01.014; 23.03.01.007; 11.07.01.005; 10.01.01.045--
Stomatitis07.05.06.005--
Superinfection11.01.08.009--Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombocytosis01.08.02.001--Not Available
Thrombophlebitis24.01.02.001--Not Available
Toxic epidermal necrolysis11.07.01.006; 10.01.01.006; 23.03.01.008; 12.03.01.015--
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
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ADReCS-Target
Drug Name ADR Term Target
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