Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Podophyllum resin
Drug ID BADD_D01791
Description Podophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum emodi_, which contains numerous compounds, amongst which is podophyllin (as well as the drug [podophyllotoxin]). Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase.
Indications and Usage 25% podophyllin (in benzoin tincture) is indicated for the removal of soft genital (venereal) warts (condylomata acuminata).
Marketing Status approved
ATC Code Not Available
DrugBank ID DB09094
KEGG ID D06484
MeSH ID D011033
PubChem ID 11979494
TTD Drug ID Not Available
NDC Product Code 49452-5480; 51927-5219; 63629-8699; 0574-0601; 51552-0016; 63570-008
UNII 16902YVY2B
Synonyms Podophyllin | Podophyllum Resin | Resin, Podophyllum
Chemical Information
Molecular Formula C88H92O34
CAS Registry Number 9000-55-9
SMILES COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O.COC1=CC(=CC(=C1OC)OC)C 2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O.COC1=CC(=CC(=C1OC)OC)C2C(C(C(C3=CC4=C(C=C23) OCO4)O)CO)C(=O)O.COC1=CC(=CC(=C1OC)OC)C2C(C(C(C3=CC4=C(C=C23)OCO4)O)CO)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Coma17.02.09.001--Not Available
Congenital anomaly03.02.01.001--Not Available
Death08.04.01.001--
Ileus paralytic07.02.05.001--Not Available
Leukopenia01.02.02.001--Not Available
Paraesthesia23.03.03.094; 17.02.06.005--
Polyneuropathy17.09.03.012--Not Available
Pyrexia08.05.02.003--
Stillbirth08.04.01.006; 18.01.02.002--Not Available
Thrombocytopenia01.08.01.002--Not Available
Foetal death08.04.01.011; 18.01.02.003--
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