Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Polythiazide
Drug ID BADD_D01797
Description A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Indications and Usage Polythiazide is a thiazide diuretic used to decrease edema and decrease blood pressure.
Marketing Status approved
ATC Code C03AA05
DrugBank ID DB01324
KEGG ID D00657
MeSH ID D011139
PubChem ID 4870
TTD Drug ID D06TNG
NDC Product Code Not Available
UNII 36780APV5N
Synonyms Polythiazide | Renese
Chemical Information
Molecular Formula C11H13ClF3N3O4S3
CAS Registry Number 346-18-9
SMILES CN1C(NC2=CC(=C(C=C2S1(=O)=O)S(=O)(=O)N)Cl)CSCC(F)(F)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Aplastic anaemia01.03.03.002--Not Available
Asthenia08.01.01.001--Not Available
Blood uric acid increased13.02.04.001--Not Available
Constipation07.02.02.001--
Cutaneous vasculitis24.12.04.008; 23.06.02.001; 10.02.02.003--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Glycosuria20.02.01.005--
Headache17.14.01.001--
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hypersensitivity10.01.03.003--
Hyperuricaemia14.09.01.003--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukopenia01.02.02.001--Not Available
Muscle spasms15.05.03.004--
Nausea07.01.07.001--
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Pancreatitis07.18.01.001--
Paraesthesia23.03.03.094; 17.02.06.005--
Photosensitivity reaction23.03.09.003--
Purpura23.06.01.004; 01.01.04.003; 24.07.06.005--
Rash23.03.13.001--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Thrombocytopenia01.08.01.002--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura01.01.04.007; 24.07.06.011; 23.06.01.008--Not Available
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