Pharmaceutical Information |
Drug Name |
Porfimer |
Drug ID |
BADD_D01802 |
Description |
The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in the United States. |
Indications and Usage |
Indicated in the treatment of esophageal cancer. |
Marketing Status |
approved; investigational |
ATC Code |
L01XD01 |
DrugBank ID |
DB00707
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KEGG ID |
D03327
|
MeSH ID |
D017323
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PubChem ID |
135577896
|
TTD Drug ID |
D02JDL
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NDC Product Code |
76128-155 |
UNII |
M15H03K69B
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Synonyms |
Dihematoporphyrin Ether | Ether, Dihematoporphyrin | Dihematoporphyrin Ester | Porfimer | DHP Ether | Porfimer Sodium | Photofrin | Photofrin II |
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Chemical Information |
Molecular Formula |
C68H74N8O11 |
CAS Registry Number |
87806-31-3 |
SMILES |
CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4C)C(C)OC(C)C6=C(C7=CC
8=C(C(=C(N8)C=C9C(=C(C(=N9)C=C1C(=C(C(=N1)C=C6N7)C)CCC(=O)O)CCC(=O)O)C)C)C(C)O)C
)C(=C3CCC(=O)O)C)CCC(=O)O |
Chemical Structure |
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ADRs Induced by Drug |
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