Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Praziquantel
Drug ID BADD_D01826
Description An anthelmintic used in most schistosome and many cestode infestations.
Indications and Usage For the treatment of infections due to all species of schistosoma.
Marketing Status approved; investigational; vet_approved
ATC Code P02BA01
DrugBank ID DB01058
KEGG ID D00471
MeSH ID D011223
PubChem ID 4891
TTD Drug ID D0L9ZR
NDC Product Code 53104-7567; 72643-005; 86055-0003; 13371-321; 71052-203; 12527-2521; 14639-0022; 62991-2053; 49169-1027; 49452-5976; 49884-231; 50419-747; 38779-0090; 10745-0422; 52562-022; 69011-0001
UNII 6490C9U457
Synonyms Praziquantel | Prasiquantel | Praziquantel, (+-)-Isomer | Praziquantel, (R)-Isomer | Praziquantel, (S)-Isomer | Drontsit | Traziquantel | Biltricide | Cesol | Cysticide | Cisticid | Droncit | EMBAY 8440 | Pyquiton
Chemical Information
Molecular Formula C19H24N2O2
CAS Registry Number 55268-74-1
SMILES C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.0020.001691%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.001691%
Anaphylactic shock24.06.02.004; 10.01.07.0020.001691%Not Available
Arrhythmia02.03.02.001--Not Available
Ascites09.01.05.003; 07.07.01.001; 02.05.04.0020.001691%
Asthenia08.01.01.001--Not Available
Atrioventricular block02.03.01.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bradycardia02.03.02.002--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.0110.001691%Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.002--Not Available
Discomfort08.01.08.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.0030.003381%
Drug ineffective08.06.01.0060.006255%Not Available
Dyspnoea02.11.05.003; 22.02.01.0040.001691%
Eosinophilia01.02.04.0010.002536%
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.0280.001691%
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001--Not Available
Malaise08.01.01.003--
Myalgia15.05.02.001--
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