Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisone
Drug ID BADD_D01834
Description A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Indications and Usage Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.[L10502]
Marketing Status approved; vet_approved
ATC Code A07EA03; H02AB07
DrugBank ID DB00635
KEGG ID D00473
MeSH ID D011241
PubChem ID 5865
TTD Drug ID D0IL7L
NDC Product Code 80425-0068; 82982-041; 0591-5052; 42291-727; 42708-105; 43063-911; 50090-0439; 50090-3361; 51655-242; 53002-0610; 55154-4950; 58118-0173; 59746-175; 60219-1707; 61919-321; 62135-471; 63187-066; 63629-2255; 63629-2263; 0378-0642; 64380-949; 67296-0138; 67296-1194; 67296-1755; 68071-2304; 68071-5242; 70518-0632; 70518-2115; 70518-2138; 71205-729; 71205-755; 71205-818; 0054-4741; 71335-1926; 0591-5443; 71335-2153; 0603-5336; 76420-068; 80425-0069; 82982-042; 10135-777; 10135-779; 50090-3137; 51655-493; 51655-763; 51655-765; 51655-779; 55154-4938; 59746-171; 60760-932; 63187-807; 63629-2254; 63629-2434; 64380-835; 66267-173; 66267-860; 67296-1444; 68071-2661; 68071-4691; 68071-5195; 68788-7372; 68788-7692; 68788-8166; 68788-9551; 70518-2675; 70518-2704; 70518-3540; 70934-880; 70954-060; 71205-741; 71335-2088; 0054-8739; 72162-1169; 72189-275; 0615-8438; 80425-0105; 64958-0002; 43063-968; 50090-6225; 51655-410; 51655-988; 53002-3090; 54348-506; 55154-4946; 55289-330; 55700-208; 60219-1705; 61919-235; 61919-365; 63629-7917; 67296-0140; 0054-0019; 68788-8212; 70954-061; 71205-089; 71335-1780; 71335-2149; 0054-8724; 0054-8740; 0054-9828; 72162-1170; 0615-8307; 0615-8441; 59651-489; 60760-002; 63629-2256; 64380-782; 67296-1183; 0054-0018; 70518-1553; 70518-2916; 70934-095; 70954-057; 71205-460; 71205-797; 71335-2122; 71335-2134; 0603-5337; 71610-721; 0054-9818; 0615-8306; 72189-489; 0615-8439; 80425-0106; 0904-6923; 13672-033; 10135-778; 43063-703; 45865-670; 53002-3252; 59746-172; 60687-145; 60760-255; 60760-790; 61919-108; 63187-085; 63629-2258; 63629-2435; 0378-0641; 68071-2209; 68071-2578; 68071-3143; 68788-6440; 68788-7752; 68788-8267; 70954-059; 71205-537; 71335-1524; 71335-1628; 71335-1736; 71335-1737; 71335-2051; 0603-5335; 0603-5339; 0615-8440; 75987-021; 75987-022; 0591-5442; 13672-032; 42708-115; 50090-3336; 51655-355; 51655-416; 51655-935; 51655-972; 59651-487; 60219-1708; 62135-470; 63187-300; 63187-997; 63629-2260; 63629-2262; 68071-1779; 68788-8116; 0527-2934; 70518-0305; 70518-0306; 70518-1120; 70882-117; 0054-4742; 71335-1516; 71335-1525; 0603-5338; 76420-067; 13672-031; 51552-0028; 10135-774; 42708-136; 50090-6123; 50090-6259; 51655-068; 51655-359; 51655-701; 53002-3091; 53002-3520; 59651-488; 60687-122; 63187-243; 63629-1579; 63629-2261; 0378-0640; 64380-784; 64380-785; 67296-0247; 67296-1065; 67296-1455; 67296-1457; 68071-2696; 68071-5196; 68071-5233; 0527-2933; 70518-1561; 70518-2676; 70518-3138; 71205-403; 71335-0464; 0615-8395; 72789-235; 0904-7127; 42708-167; 50090-3330; 50090-3354; 50090-5816; 51407-356; 51407-360; 51655-726; 55154-4949; 59651-484; 60760-715; 63629-2257; 68071-2781; 68788-8184; 0527-2930; 70518-0307; 70518-2555; 70518-3142; 70934-096; 70954-056; 71205-407; 71335-0623; 0054-4728; 0054-9817; 72162-1171; 75987-020; 10135-776; 60722-1002; 82298-103; 42291-771; 42708-114; 42708-166; 51655-349; 51655-760; 59651-486; 59746-173; 60219-1706; 60760-615; 63187-037; 67296-1083; 67296-1446; 67544-399; 0054-0017; 70518-3537; 70934-291; 0054-3722; 71205-362; 71335-0335; 71335-0508; 71335-2079; 71610-641; 72162-1172; 72189-246; 80425-0193; 38779-0154; 57582-003; 42708-045; 43063-866; 50090-6122; 51407-355; 51407-357; 51655-197; 51655-541; 51655-716; 53002-3250; 55700-203; 55700-209; 60687-134; 61919-326; 63187-020; 63629-1605; 63629-2259; 63629-2264; 63739-588; 64380-783; 67296-1203; 67296-1767; 67296-1886; 68071-2771; 70518-2314; 70518-2703; 70518-3401; 70518-3476; 70518-3539; 70518-3555; 70954-058; 71205-239; 71205-421; 71205-665; 71335-1915; 71335-2069; 71335-2160; 71335-9715; 72189-430; 0615-8391; 76420-069; 49452-6000; 10135-775; 42291-770; 42291-783; 50090-4785; 50090-5814; 50090-6376; 51407-358; 51407-359; 51655-208; 51655-939; 55154-3564; 58118-5442; 59651-485
UNII VB0R961HZT
Synonyms Prednisone | Dehydrocortisone | delta-Cortisone | Rectodelt | Prednison Hexal | Sterapred | Ultracorten | Winpred | Apo-Prednisone | Cortan | Cortancyl | Panafcort | Cutason | Decortin | Dacortin | Decortisyl | Deltasone | Encortone | Encorton | Enkortolon | Kortancyl | Liquid Pred | Meticorten | Orasone | Panasol | Predni Tablinen | Prednidib | Predniment | Prednison Acsis | Acsis, Prednison | Pronisone | Sone | Prednison Galen
Chemical Information
Molecular Formula C21H26O5
CAS Registry Number 53-03-2
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Urinary tract obstruction20.08.01.004--
Ulcer haemorrhage24.07.01.040; 08.03.06.0030.000018%Not Available
Blood disorder01.05.01.0040.000009%Not Available
Immunodeficiency10.03.02.0020.000022%Not Available
Adverse drug reaction08.06.01.009--Not Available
Autoimmune disorder10.04.04.0030.000009%
Bone lesion15.02.04.0160.000013%Not Available
Disease progression08.01.03.0380.000461%
Disease recurrence08.01.03.0500.000633%Not Available
Diverticular perforation07.04.04.0080.000009%Not Available
Drug intolerance08.06.01.0130.000205%Not Available
Obstruction08.01.03.0230.000018%Not Available
Obstructive airways disorder22.03.01.0110.000022%Not Available
Psychotic disorder19.03.01.0020.000117%
Pulmonary toxicity22.01.02.007; 12.03.01.0130.000036%Not Available
Food intolerance14.02.01.005--Not Available
Gastrointestinal obstruction07.13.01.0050.000018%Not Available
Immunosuppression10.03.02.0010.000094%Not Available
Lung neoplasm22.08.01.006; 16.19.04.0010.000009%Not Available
Hyperlipidaemia14.08.03.0010.000018%
Pigmentation disorder23.05.03.001--Not Available
Nasal disorder22.04.03.0040.000009%Not Available
Tympanic membrane disorder04.05.04.002--Not Available
Sinus disorder22.04.06.0020.000018%
Lipohypertrophy23.07.01.005; 14.08.04.0090.000044%
Unevaluable event08.01.03.051--Not Available
Poor quality sleep17.15.04.002; 19.02.05.0050.000044%Not Available
Increased bronchial secretion22.12.01.002--Not Available
Middle ear effusion04.05.03.001--Not Available
Peripheral arterial occlusive disease24.04.03.0100.000009%Not Available
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