Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prednisone
Drug ID BADD_D01834
Description A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Indications and Usage Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.[L10502]
Marketing Status approved; vet_approved
ATC Code A07EA03; H02AB07
DrugBank ID DB00635
KEGG ID D00473
MeSH ID D011241
PubChem ID 5865
TTD Drug ID D0IL7L
NDC Product Code 80425-0068; 82982-041; 0591-5052; 42291-727; 42708-105; 43063-911; 50090-0439; 50090-3361; 51655-242; 53002-0610; 55154-4950; 58118-0173; 59746-175; 60219-1707; 61919-321; 62135-471; 63187-066; 63629-2255; 63629-2263; 0378-0642; 64380-949; 67296-0138; 67296-1194; 67296-1755; 68071-2304; 68071-5242; 70518-0632; 70518-2115; 70518-2138; 71205-729; 71205-755; 71205-818; 0054-4741; 71335-1926; 0591-5443; 71335-2153; 0603-5336; 76420-068; 80425-0069; 82982-042; 10135-777; 10135-779; 50090-3137; 51655-493; 51655-763; 51655-765; 51655-779; 55154-4938; 59746-171; 60760-932; 63187-807; 63629-2254; 63629-2434; 64380-835; 66267-173; 66267-860; 67296-1444; 68071-2661; 68071-4691; 68071-5195; 68788-7372; 68788-7692; 68788-8166; 68788-9551; 70518-2675; 70518-2704; 70518-3540; 70934-880; 70954-060; 71205-741; 71335-2088; 0054-8739; 72162-1169; 72189-275; 0615-8438; 80425-0105; 64958-0002; 43063-968; 50090-6225; 51655-410; 51655-988; 53002-3090; 54348-506; 55154-4946; 55289-330; 55700-208; 60219-1705; 61919-235; 61919-365; 63629-7917; 67296-0140; 0054-0019; 68788-8212; 70954-061; 71205-089; 71335-1780; 71335-2149; 0054-8724; 0054-8740; 0054-9828; 72162-1170; 0615-8307; 0615-8441; 59651-489; 60760-002; 63629-2256; 64380-782; 67296-1183; 0054-0018; 70518-1553; 70518-2916; 70934-095; 70954-057; 71205-460; 71205-797; 71335-2122; 71335-2134; 0603-5337; 71610-721; 0054-9818; 0615-8306; 72189-489; 0615-8439; 80425-0106; 0904-6923; 13672-033; 10135-778; 43063-703; 45865-670; 53002-3252; 59746-172; 60687-145; 60760-255; 60760-790; 61919-108; 63187-085; 63629-2258; 63629-2435; 0378-0641; 68071-2209; 68071-2578; 68071-3143; 68788-6440; 68788-7752; 68788-8267; 70954-059; 71205-537; 71335-1524; 71335-1628; 71335-1736; 71335-1737; 71335-2051; 0603-5335; 0603-5339; 0615-8440; 75987-021; 75987-022; 0591-5442; 13672-032; 42708-115; 50090-3336; 51655-355; 51655-416; 51655-935; 51655-972; 59651-487; 60219-1708; 62135-470; 63187-300; 63187-997; 63629-2260; 63629-2262; 68071-1779; 68788-8116; 0527-2934; 70518-0305; 70518-0306; 70518-1120; 70882-117; 0054-4742; 71335-1516; 71335-1525; 0603-5338; 76420-067; 13672-031; 51552-0028; 10135-774; 42708-136; 50090-6123; 50090-6259; 51655-068; 51655-359; 51655-701; 53002-3091; 53002-3520; 59651-488; 60687-122; 63187-243; 63629-1579; 63629-2261; 0378-0640; 64380-784; 64380-785; 67296-0247; 67296-1065; 67296-1455; 67296-1457; 68071-2696; 68071-5196; 68071-5233; 0527-2933; 70518-1561; 70518-2676; 70518-3138; 71205-403; 71335-0464; 0615-8395; 72789-235; 0904-7127; 42708-167; 50090-3330; 50090-3354; 50090-5816; 51407-356; 51407-360; 51655-726; 55154-4949; 59651-484; 60760-715; 63629-2257; 68071-2781; 68788-8184; 0527-2930; 70518-0307; 70518-2555; 70518-3142; 70934-096; 70954-056; 71205-407; 71335-0623; 0054-4728; 0054-9817; 72162-1171; 75987-020; 10135-776; 60722-1002; 82298-103; 42291-771; 42708-114; 42708-166; 51655-349; 51655-760; 59651-486; 59746-173; 60219-1706; 60760-615; 63187-037; 67296-1083; 67296-1446; 67544-399; 0054-0017; 70518-3537; 70934-291; 0054-3722; 71205-362; 71335-0335; 71335-0508; 71335-2079; 71610-641; 72162-1172; 72189-246; 80425-0193; 38779-0154; 57582-003; 42708-045; 43063-866; 50090-6122; 51407-355; 51407-357; 51655-197; 51655-541; 51655-716; 53002-3250; 55700-203; 55700-209; 60687-134; 61919-326; 63187-020; 63629-1605; 63629-2259; 63629-2264; 63739-588; 64380-783; 67296-1203; 67296-1767; 67296-1886; 68071-2771; 70518-2314; 70518-2703; 70518-3401; 70518-3476; 70518-3539; 70518-3555; 70954-058; 71205-239; 71205-421; 71205-665; 71335-1915; 71335-2069; 71335-2160; 71335-9715; 72189-430; 0615-8391; 76420-069; 49452-6000; 10135-775; 42291-770; 42291-783; 50090-4785; 50090-5814; 50090-6376; 51407-358; 51407-359; 51655-208; 51655-939; 55154-3564; 58118-5442; 59651-485
UNII VB0R961HZT
Synonyms Prednisone | Dehydrocortisone | delta-Cortisone | Rectodelt | Prednison Hexal | Sterapred | Ultracorten | Winpred | Apo-Prednisone | Cortan | Cortancyl | Panafcort | Cutason | Decortin | Dacortin | Decortisyl | Deltasone | Encortone | Encorton | Enkortolon | Kortancyl | Liquid Pred | Meticorten | Orasone | Panasol | Predni Tablinen | Prednidib | Predniment | Prednison Acsis | Acsis, Prednison | Pronisone | Sone | Prednison Galen
Chemical Information
Molecular Formula C21H26O5
CAS Registry Number 53-03-2
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arterial occlusive disease24.04.02.021--Not Available
Increased upper airway secretion22.12.03.007--Not Available
Retinal pigment epithelial tear06.09.03.0160.000018%Not Available
Chorioretinopathy06.09.01.0060.000089%Not Available
Chronic allograft nephropathy20.01.02.010; 12.02.10.005; 10.02.03.0040.000009%Not Available
Metamorphopsia17.17.01.020; 06.02.06.0140.000018%Not Available
Bowel movement irregularity07.02.03.0030.000013%Not Available
Erosive oesophagitis07.04.05.0040.000009%Not Available
Hypophagia19.09.01.004; 14.03.01.006; 07.01.06.0100.000047%Not Available
Gastrointestinal inflammation07.08.03.0070.000042%Not Available
Skin haemorrhage24.07.01.103; 23.06.07.0010.000033%Not Available
Osteonecrosis of jaw24.04.05.005; 15.02.04.0100.000107%
Infusion site extravasation12.07.05.008; 08.02.05.0070.000018%
Chronic kidney disease20.01.03.0170.000085%
Ulcerative keratitis10.02.01.021; 06.04.02.0040.000020%
Immune reconstitution inflammatory syndrome10.02.01.043; 08.06.02.0140.000045%Not Available
Infusion site haemorrhage24.07.01.058; 12.07.05.018; 08.02.05.018--Not Available
Bone marrow failure01.03.03.0050.000063%
Loose tooth07.09.05.0090.000027%Not Available
Bone loss15.02.04.020--Not Available
Pharyngeal inflammation22.04.05.0080.000009%
Central obesity14.03.02.0110.000009%Not Available
Injection site papule23.03.03.045; 12.07.03.031; 08.02.03.0310.000076%Not Available
Acute graft versus host disease12.02.09.002; 10.02.01.0280.000009%Not Available
Chronic graft versus host disease10.02.01.029; 12.02.09.0030.000009%Not Available
Tendon pain15.07.01.0090.000044%Not Available
Haematological malignancy16.21.01.002; 01.13.01.0030.000009%Not Available
Treatment failure08.06.01.0170.000383%Not Available
Liver injury12.01.17.012; 09.01.07.0220.000036%Not Available
Regurgitation07.01.07.004--Not Available
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