| Pharmaceutical Information |
| Drug Name |
Probenecid |
| Drug ID |
BADD_D01841 |
| Description |
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. |
| Indications and Usage |
For the reduction of serum uric acid concentrations in chronic gouty arthritis and tophaceous gout in patients with frequent disabling gout attacks. Has also been effectively used to promote uric acid excretion in hyperuricemia secondary to the administration of thiazide and related diuretics. |
| Marketing Status |
approved; investigational |
| ATC Code |
M04AB01 |
| DrugBank ID |
DB01032
|
| KEGG ID |
D00475
|
| MeSH ID |
D011339
|
| PubChem ID |
4911
|
| TTD Drug ID |
D0L7FM
|
| NDC Product Code |
63415-0026; 0591-5347; 10135-541; 0527-1367; 38779-0345; 43235-0015; 71335-1697; 83008-020; 68022-7061 |
| UNII |
PO572Z7917
|
| Synonyms |
Probenecid | Probenecid Weimer | Pro-Cid | Probecid | Benuryl | Benecid | Benemid |
|
| Chemical Information |
| Molecular Formula |
C13H19NO4S |
| CAS Registry Number |
57-66-9 |
| SMILES |
CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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