| Pharmaceutical Information |
| Drug Name |
Proparacaine hydrochloride |
| Drug ID |
BADD_D01863 |
| Description |
Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt. |
| Indications and Usage |
Used as a local (ophthalmic) anesthetic. |
| Marketing Status |
approved; vet_approved |
| ATC Code |
S01HA04 |
| DrugBank ID |
DB00807
|
| KEGG ID |
D02098
|
| MeSH ID |
C005717
|
| PubChem ID |
517321
|
| TTD Drug ID |
D0Q7ZG
|
| NDC Product Code |
0998-0016; 61314-016; 68071-4368; 0404-7199; 51552-1450; 17478-263; 50090-1923; 70518-3408; 13985-611; 24208-730; 17205-340; 76003-3500 |
| UNII |
U96OL57GOY
|
| Synonyms |
proxymetacaine | benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester | proparacaine | proxymethacaine | 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate | Alcaine | Chibro-Kerakain | Kainair | Kéracaine | proxymetacaine hydrochloride | proparacaine HCl | proxymetacaine monohydrochloride | benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride*benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride | proparacaine hydrochloride | 2-(diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride | Ocu-Caine | Ophthaine | Ophthetic | Parcaine | Proparakain-POS | AK-Taine | Minims Proxymetacaine Hydrochloride |
|
| Chemical Information |
| Molecular Formula |
C16H27ClN2O3 |
| CAS Registry Number |
5875-06-9 |
| SMILES |
CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Burning sensation | 17.02.06.001; 08.01.09.029 | - | - | Not Available | | Dermatitis contact | 10.01.01.003; 23.03.04.004; 12.03.01.040 | - | - | Not Available | | Iritis | 10.02.01.022; 06.04.03.002 | - | - | Not Available | | Keratitis | 06.04.02.002 | - | - | | | Pain | 08.01.08.004 | - | - | | | Conjunctival hyperaemia | 06.04.01.004 | - | - | Not Available |
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