| Pharmaceutical Information |
| Drug Name |
Propoxyphene |
| Drug ID |
BADD_D01865 |
| Description |
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect. The levo-isomer appears to exhibit a very limited antitussive effect. |
| Indications and Usage |
For the relief of mild to moderate pain. |
| Marketing Status |
approved; illicit; investigational; withdrawn |
| ATC Code |
N02AC04 |
| DrugBank ID |
DB00647
|
| KEGG ID |
D00482; D07809
|
| MeSH ID |
D011431
|
| PubChem ID |
10100
|
| TTD Drug ID |
D0D4PB
|
| NDC Product Code |
Not Available |
| UNII |
S2F83W92TK
|
| Synonyms |
Dextropropoxyphene | Propoxyphene | D-Propoxyphene | D Propoxyphene | Propoxyphene Hydrochloride | Hydrochloride, Propoxyphene | Propoxyphene Hydrochloride, (R*,R*)-(+-)-Isomer | Propoxyphene Sulfate, (S-(R*,S*))-Isomer | Propoxyphene Hydrochloride, (R-(R*,S*))-Isomer | Propoxyphene Hydrochloride, (S-(R*,R*))-Isomer | Propoxyphene Maleate, (+)-Isomer | Propoxyphene Phosphate, (S-(R*,S*))-Isomer | Darvon | Propoxyphene Hydrochloride, (R-(R*,R*))-Isomer |
|
| Chemical Information |
| Molecular Formula |
C22H29NO2 |
| CAS Registry Number |
469-62-5 |
| SMILES |
CCC(=O)OC(CC1=CC=CC=C1)(C2=CC=CC=C2)C(C)CN(C)C |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
