| Pharmaceutical Information |
| Drug Name |
Prussian blue |
| Drug ID |
BADD_D01875 |
| Description |
Prussian blue is described as a deep blue pigment that is produced when the oxidation of ferrous ferrocyanide salts occurs. It contains ferric hexacyanoferrate(II) in a cubic lattice crystal structure. It is insoluble in water but also tends to form a colloid thus can exist in either colloidal or water-soluble form, and an insoluble form. It is orally administered for clinical purposes to be used as an antidote for certain kinds of heavy metal poisoning, such as thallium and radioactive isotopes of caesium. Prussian blue is included in the World Health Organization Model List of Essential Medicines as a specific antidote used in poisonings to provide symptomatic and supportive treatment. It was also administered in individuals exposed to 137-Cs+ during Goiânia accident, one of the worst radioactive contamination incidents that occured in Brazil, 1983. |
| Indications and Usage |
Indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination. |
| Marketing Status |
approved |
| ATC Code |
V03AB31 |
| DrugBank ID |
DB06783
|
| KEGG ID |
Not Available
|
| MeSH ID |
C000170
|
| PubChem ID |
2724251
|
| TTD Drug ID |
D0M3TM
|
| NDC Product Code |
Not Available |
| UNII |
Not Available
|
| Synonyms |
ferric ferrocyanide | ferrocin | ferrotsin | Prussian blue | Berlin blue | ferrihexacyanoferrate |
|
| Chemical Information |
| Molecular Formula |
Fe4[Fe(CN)6]3 |
| CAS Registry Number |
14038-43-8 |
| SMILES |
[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-
]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[Fe+2].[Fe+2].[Fe+2].[Fe+3].[Fe+3]
.[Fe+3].[Fe+3] |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Constipation | 07.02.02.001 | - | - | |
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